Mapping Neutrophil Fate and Function in Ischemic Stroke: A Single-cell Roadmap for Translational Insights

Abstract excerpt

<title>Abstract</title> <p>Background Ischemic stroke (IS) accounts for 71% of all strokes, whose diagnosis and prognosis require further exploration. Neutrophil extracellular traps (NETs) are produced by neutrophils, and there is already evidence that NETs play a role in IS, but further studies about crosstalk between immune cells, pathways and NETs are still needed. Materials and Methods To assess the express...

Topics

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• Acute Ischemic Stroke Management
• Intracranial Aneurysms: Treatment and Complications
• Neuroinflammation and Neurodegeneration Mechanisms
• Neutrophil, Myeloperoxidase and Oxidative Mechanisms
• S100 Proteins and Annexins
• Single-cell and spatial transcriptomics

Identifiers and source

Literature Corpus work

7ee9d6f6-77db-55db-bb6f-581d053edffb

DOI

10.21203/rs.3.rs-5300274/v1