Article

MAX precision test of the Genome-wide association study under two-stage design

2023-11-20

Abstract excerpt

<title>Abstract</title> <p>One of the important topics in genetic statistics and medical research is the study of human complex diseases caused by multiple genes. With the development and completion of the Human Genome Project, many complex diseases have been discovered, and scientists have also identified some disease-causing genes, providing assistance and direction for the prevention, diagnosis, and treatment...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ed16e6c5-27ba-5924-843e-a0dece59a970
DOI: 10.21203/rs.3.rs-3595446/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MAX precision test of the Genome-wide association study under two-stage designDOI 10.21203/rs.3.rs-3595446/v1Read

Robust joint analysis allowing for model uncertainty in two-stage genetic association studies.Semantic proximity Read

Efficient approximation of P-value of the maximum of correlated tests, with applications to genome-wide association studies.Semantic proximity Read

MAX-rank: a simple and robust genome-wide scan for case-control association studies.Semantic proximity Read

A unifying framework for robust association testing, estimation, and genetic model selection using the generalized linear model.Semantic proximity Read

Screening properties of trend tests in genetic association studies.Semantic proximity Read

Pearson's test, trend test, and MAX are all trend tests with different types of scores.Semantic proximity Read

A robust test for two-stage design in genome-wide association studies.Semantic proximity Read

Robust tests for single-marker analysis in case-control genetic association studies.Semantic proximity Read

A robust genome-wide scan statistic of the Wellcome Trust Case-Control Consortium.Semantic proximity Read

Optimization of two-stage genetic designs where data are combined using an accurate and efficient approximation for Pearson's statistic.Semantic proximity Read

A robust method for testing association in genome-wide association studies.Semantic proximity Read

Power estimation of multiple SNP association test of case-control study and application.Semantic proximity Read