Article
Robust tests for single-marker analysis in case-control genetic association studies.
Annals of human genetics - 1 Mar 2009
Li Qizhai, Zheng Gang, Liang Xueying, Yu Kai
Abstract excerpt
Choosing an appropriate single-marker association test is critical to the success of case-control genetic association studies.An ideal single-marker analysis should have robust performance across a wide range of potential disease risk models. MAX was designed specifically to achieve such robustness. In this work, we derived the power calculation formula for MAX and conducted a comprehensive power comparison...
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