Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Screening properties of trend tests in genetic association studies.

Scientific reports - 5 Jun 2023

Jiang Zhenzhen, Guo Hongping, Wang Jinjuan

Abstract excerpt

In genome-wide association study, extracting disease-associated genetic variants among millions of single nucleotide polymorphisms is of great importance. When the response is a binary variable, the Cochran-Armitage trend tests and associated MAX test are among the most widely used methods for association analysis. However, the theoretical guarantees for applying these methods to variable screening have not been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Case-Control Studies
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Models, Genetic

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 37277435
DOI: 10.1038/s41598-023-35929-4
PMCID: PMC10241885

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Screening properties of trend tests in genetic association studies.PMID 37277435Read ↗

MAX precision test of the Genome-wide association study under two-stage designSemantic proximity Read ↗

Efficient approximation of P-value of the maximum of correlated tests, with applications to genome-wide association studies.Semantic proximity Read ↗

MAX-rank: a simple and robust genome-wide scan for case-control association studies.Semantic proximity Read ↗

Pearson's test, trend test, and MAX are all trend tests with different types of scores.Semantic proximity Read ↗

A unifying framework for robust association testing, estimation, and genetic model selection using the generalized linear model.Semantic proximity Read ↗

Use of max and min scores for trend tests for association when the genetic model is unknown.Semantic proximity Read ↗

Robust Mantel-Haenszel test under genetic model uncertainty allowing for covariates in case-control association studies.Semantic proximity Read ↗

A robust method for testing association in genome-wide association studies.Semantic proximity Read ↗

GWAR: robust analysis and meta-analysis of genome-wide association studies.Semantic proximity Read ↗

Detecting PCOS susceptibility loci from genome-wide association studies via iterative trend correlation based feature screening.Semantic proximity Read ↗

A robust genome-wide scan statistic of the Wellcome Trust Case-Control Consortium.Semantic proximity Read ↗

Robust tests for single-marker analysis in case-control genetic association studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.