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The expanding Pandora’s toolbox of CD8+T cell: from transcriptional control to metabolic firing

11 Dec 2023

Abstract excerpt

Abstract CD8+ T cells are the executor in adaptive immune response, especially in anti-tumor immunity. They are the subset immune cells that are of high plasticity and multifunction. Their development, differentiation, activation and metabolism are delicately regulated by multiple factors. Stimuli from the internal and external environment could remodel CD8+ T cells, and correspondingly they will also make...

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PMID: 38082437
DOI: 10.1186/s12967-023-04775-3

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