Article
T-cell immunometabolism against cancer.
Cancer letters - 28 Nov 2016
Jiang Shuai, Yan Wei
Abstract excerpt
T cells play critical roles in host defenses against cancer. External signals prompt activation of naïve T cells, triggering modulation of their immune functions. Emerging evidence reveals that distinct metabolic changes impact the immune functions of naïve and effector T cells, including CD4+ and CD8+ T cells. Since T cells appear to be key players in tumor progression, it is important to elucidate whether and...
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