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Metabolic Reprogramming and Longevity of Tissue-Resident Memory T Cells

18 Jun 2018

Abstract excerpt

Tissue-resident memory T cells (TRM) persist in peripheral tissues for long periods of time in the absence of antigenic stimulation. Upon re-encounter with cognate antigen, TRM trigger an immediate immune response at the local tissue microenvironment and provide the first line of host defense. TRM have been reported to play significant roles in host anti-microbial infection, cancer immunotherapy and pathogenesis...

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Identifiers

PMID: 29967608
DOI: 10.3389/fimmu.2018.01347

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