Article
Serum Flt3 ligand is biomarker of progenitor cell mass and prognosis in acute myeloid leukemia
2019-03-25
Abstract excerpt
Fms-like tyrosine kinase 3 (Flt3) is a hematopoietic growth factor receptor expressed on lymphomyeloid progenitors and frequently, by AML blasts. Its ligand, Flt3L, has non-hematopoietic and lymphoid origins, is detectable during homeostasis and increases to high levels in states of hypoplasia due to genetic defects or treatment with cytoreductive agents. Measurement of Flt3L by ELISA reveals that Flt3 + AML, is...
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Identifiers and source
- Literature Corpus work
- ed003187-da82-5b12-b2cd-a985c5f1bba3
- DOI
- 10.1101/588319