FLT3 ligand in acute myeloid leukemia: a simple test with deep implications.

doi:10.1080/10428194.2020.1834091

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Article

FLT3 ligand in acute myeloid leukemia: a simple test with deep implications.

Leukemia & lymphoma - 1 Feb 2021

Peterlin Pierre, Chevallier Patrice, Knapper Steven, Collin Matthew

Abstract excerpt

In contrast to Fms-like tyrosine kinase 3 (FLT3), the influence of FLT3 ligand (FLT3L) on acute myeloid leukemia (AML) biology and disease prognosis has been poorly described. Here we provide an overview of the role played by FLT3L in AML. While being a cytokine implicated in the regulation of he...

Topics

Hematopoiesis
Humans
Leukemia, Myeloid, Acute
Membrane Proteins
Mutation
Prognosis
fms-Like Tyrosine Kinase 3

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