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Article

The roles of FLT3 in hematopoiesis and leukemia.

Blood - 1 Sept 2002

Gilliland D Gary, Griffin James D

Abstract excerpt

FLT3 is a receptor tyrosine kinase expressed by immature hematopoietic cells and is important for the normal development of stem cells and the immune system. The ligand for FLT3 is expressed by marrow stromal cells and other cells and synergizes with other growth factors to stimulate proliferation of stem cells, progenitor cells, dendritic cells, and natural killer cells. Mutations of FLT3 have been detected in...

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Source

Identifiers

PMID: 12176867
DOI: 10.1182/blood-2002-02-0492

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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