An Update on FLT3 in Acute Myeloid Leukemia: Pathophysiology and Therapeutic Landscape.

doi:10.1007/s11912-023-01389-2

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Article

An Update on FLT3 in Acute Myeloid Leukemia: Pathophysiology and Therapeutic Landscape.

Current oncology reports - 1 Apr 2023

Bystrom Rebecca, Levis Mark J

Abstract excerpt

PURPOSE OF REVIEW: This review aims to summarize the pathophysiology, clinical presentation, and management of acute myeloid leukemia (AML) with FMS-like tyrosine kinase-3 (FLT3) mutations. RECENT FINDINGS: The recent European Leukemia Net (ELN2022) recommendations re-classified AML with FLT3 int...

Topics

Humans
Nuclear Proteins
Nucleophosmin
Leukemia, Myeloid, Acute
Mutation
Hematopoietic Stem Cell Transplantation
fms-Like Tyrosine Kinase 3
Prognosis

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