Article
FLT3 inhibition as a targeted therapy for acute myeloid leukemia.
Current opinion in oncology - 1 Nov 2009
Sanz Miguel, Burnett Alan, Lo-Coco Francesco, Löwenberg Bob
Abstract excerpt
PURPOSE OF REVIEW: The management of acute myeloid leukemia (AML) presents significant challenges, and there remains a need for new therapies with greater efficacy and better tolerability than existing treatments. An improved understanding of the genetic and molecular changes underlying AML can help both to guide treatment strategies and to predict clinical outcomes, thereby enabling more precise decision-making...
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