Article
The Gut-Liver Axis in Primary Sclerosing Cholangitis.
Clinics in liver disease - 1 Feb 2016
Eksteen Bertus
Abstract excerpt
Dysregulation of the key genetic, immunologic, and microbiome compounds of the gut-liver axis is the basis for inflammatory bowel disease (IBD) and primary sclerosing cholangitis (PSC). This creates opportunities to accelerate therapies that have been traditionally developed for IBD to be used in PSC to the benefit of both diseases. Shared genetic susceptibility loci has yielded important clues into the...
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