Article

Antigen-driven colonic inflammation is associated with development of dysplasia in primary sclerosing cholangitis

2022-06-01

Abstract excerpt

<title>Abstract</title> <p>Primary sclerosing cholangitis (PSC) is an autoimmune-like disease of the bile ducts that co-occurs with inflammatory bowel disease (IBD) in almost 90% of cases. Colorectal cancer is a major complication of patients with both PSC and IBD, and these patients are at a much greater risk compared to patients with IBD without concomitant PSC. Combining flow cytometry, bulk and single cell tr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d2ac1a3b-e18c-5cff-a707-10f37420df59
DOI: 10.21203/rs.3.rs-1697242/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Antigen-driven colonic inflammation is associated with development of dysplasia in primary sclerosing cholangitisDOI 10.21203/rs.3.rs-1697242/v1Read

Distinct phenotype of primary sclerosing cholangitis-associated inflammatory bowel disease.Semantic proximity Read

Inflammatory Bowel Disease in patients with Primary Sclerosing Cholangitis: a distinct form of colitisSemantic proximity Read

Inflammatory bowel disease and primary sclerosing cholangitis: immunological links and clinical outlook.Semantic proximity Read

A Pilot Integrative Analysis of Colonic Gene Expression, Gut Microbiota, and Immune Infiltration in Primary Sclerosing Cholangitis-Inflammatory Bowel Disease: Association of Disease With Bile Acid PathwaysSemantic proximity Read

The primary sclerosing cholangitis and ulcerative colitis colonic mucosa defined through paired microbial and single-cell RNA sequencingSemantic proximity Read

Peripheral players and gut bacteria modulate inflammatory bowel disease phenotype in patients with primary sclerosing cholangitisSemantic proximity Read

Primary sclerosing cholangitis.Semantic proximity Read

Tissue-dependent transcriptional and bacterial associations in primary sclerosing cholangitis-associated inflammatory bowel diseaseSemantic proximity Read

Immunogenetics in primary sclerosing cholangitis.Semantic proximity Read

Distinctive inflammatory bowel disease phenotype in primary sclerosing cholangitis.Semantic proximity Read

Primary sclerosing cholangitis - a comprehensive review.Semantic proximity Read

The Gut-Liver Axis in Primary Sclerosing Cholangitis.Semantic proximity Read