Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Whole blood RNA sequencing identifies transcriptional differences between primary sclerosing cholangitis and ulcerative colitis

19 Dec 2023

Abstract excerpt

Background & Aims Genetic and microbiome studies across patients with primary sclerosing cholangitis (PSC) and ulcerative colitis (UC) have indicated that UC in PSC is a separate disease entity to primary UC, but expression studies for PSC are lacking. Methods We conducted whole blood RNA sequencing experiments for 495 patients with UC, 220 patients with PSC (including 177 with UC), and 320 healthy controls from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Inflammatory Bowel Disease
Share to Liver Diseases and Immunity
Share to Microscopic Colitis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38304234
DOI: 10.1016/j.jhepr.2023.100988

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Whole blood RNA sequencing identifies transcriptional differences between primary sclerosing cholangitis and ulcerative colitisPMID 38304234Read ↗

Circulating cell-free messenger RNA secretome characterization of primary sclerosing cholangitisSemantic proximity Read ↗

Inflammatory Bowel Disease in patients with Primary Sclerosing Cholangitis: a distinct form of colitisSemantic proximity Read ↗

Liver transcriptome analysis reveals PSC-attributed gene set associated with fibrosis progressionSemantic proximity Read ↗

Tissue-dependent transcriptional and bacterial associations in primary sclerosing cholangitis-associated inflammatory bowel diseaseSemantic proximity Read ↗

A Pilot Integrative Analysis of Colonic Gene Expression, Gut Microbiota, and Immune Infiltration in Primary Sclerosing Cholangitis-Inflammatory Bowel Disease: Association of Disease With Bile Acid PathwaysSemantic proximity Read ↗

The primary sclerosing cholangitis and ulcerative colitis colonic mucosa defined through paired microbial and single-cell RNA sequencingSemantic proximity Read ↗

Bioinformatics Analysis Reveals shared molecular pathways for Relationship between Ulcerative Colitis and Primary Sclerosing CholangitisSemantic proximity Read ↗

A Fibrosis‐Independent Hepatic Transcriptomic Signature Identifies Drivers of Disease Progression in Primary Sclerosing CholangitisSemantic proximity Read ↗

Single-cell and spatial transcriptomics reveals the human liver immunological landscape and myeloid dysfunction in PSCSemantic proximity Read ↗

Concordance between gene expression in peripheral whole blood and colonic tissue in children with inflammatory bowel diseaseSemantic proximity Read ↗

Rare Comorbidity between Inflammatory Bowel Disease and Primary Biliary Cholangitis: Evidence from Causality, Shared Genetic Architecture and TranscriptomicsSemantic proximity Read ↗

Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.