Article

netCRS: Network-based comorbidity risk score for prediction of myocardial infarction using biobank-scaled PheWAS data

2021-10-14

Abstract excerpt

The polygenic risk score (PRS) can help to identify individuals’ genetic susceptibility for various diseases by combining patient genetic profiles and identified single-nucleotide polymorphisms (SNPs) from genome-wide association studies. Although multiple diseases will usually afflict patients at once or in succession, conventional PRSs fail to consider genetic relationships across multiple diseases. Even multi-t...

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Literature Corpus work: ecafc528-3351-5e2e-bce9-8b80cbbe881c
DOI: 10.1101/2021.10.12.464134

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