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Article

netCRS: Network-based comorbidity risk score for prediction of myocardial infarction using biobank-scaled PheWAS data.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2000

Nam Yonghyun, Jung Sang-Hyuk, Verma Anurag, Sriram Vivek, Won Hong-Hee, Yun Jae-Seung, Kim Dokyoon

Abstract excerpt

The polygenic risk score (PRS) can help to identify individuals' genetic susceptibility for various diseases by combining patient genetic profiles and identified single-nucleotide polymorphisms (SNPs) from genome-wide association studies. Although multiple diseases will usually afflict patients at once or in succession, conventional PRSs fail to consider genetic relationships across multiple diseases. Even...

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PMID: 34890160
PMCID: PMC8682919

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