Article

Generation of pulmonary neuro-endocrine cells and tumors resembling small cell lung cancers from human embryonic stem cells

2018-02-07

Abstract excerpt

<h4>SUMMARY</h4> By blocking an important signaling pathway (called NOTCH) and interfering with expression of two tumor suppressor genes in cells derived from human embryonic stem cells, the authors have developed a model for studying highly lethal small cell lung cancers. <h4>ABSTRACT</h4> Cell culture models based on directed differentiation of human embryonic stem cells (hESCs) may reveal why certain constell...

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Literature Corpus work: eca441c3-4548-576b-a8c1-e7b4f3108aeb
DOI: 10.1101/261461

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