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Article

Human embryonic stem cells differentiated to lung lineage-specific cells ameliorate pulmonary fibrosis in a xenograft transplant mouse model.

PloS one - 1 Jan 2012

Banerjee Ena Ray, Laflamme Michael A, Papayannopoulou Thalia, Kahn Michael, Murry Charles E, Henderson William R

Abstract excerpt

BACKGROUND: Our aim was to differentiate human (h) embryonic stem (ES) cells into lung epithelial lineage-specific cells [i.e., alveolar epithelial type I (AEI) and type II (AEII) cells and Clara cells] as the first step in the development of cell-based strategies to repair lung injury in the bleomycin mouse model of idiopathic pulmonary fibrosis (IPF). A heterogeneous population of non-ciliated lung...

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Identifiers

PMID: 22470441
DOI: 10.1371/journal.pone.0033165
PMCID: PMC3314647

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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