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Article

Extracellular vesicles shed by follicular lymphoma B cells promote polarization of the bone marrow stromal cell niche.

Blood - 8 Jul 2021

Dumontet Erwan, Pangault Céline, Roulois David, Desoteux Matthis, Léonard Simon, Marchand Tony, Latour Maelle, Legoix Patricia, Loew Damarys, Dingli Florent, Dulong Joelle, Flecher Erwan, Coulouarn Cédric, Cartron Guillaume, Fest Thierry, Tarte Karin

Abstract excerpt

Follicular lymphoma (FL) originates in the lymph nodes (LNs) and infiltrates bone marrow (BM) early in the course of the disease. BM FL B cells are characterized by a lower cytological grade, decreased proliferation, and a specific phenotypic and subclonal profile. Mesenchymal stromal cells (MSCs) obtained from FL BM display a specific gene expression profile (GEP), including enrichment for a lymphoid stromal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33881493
DOI: 10.1182/blood.2020008791

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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