Article
The follicular lymphoma epigenome regulates its microenvironment.
Journal of experimental & clinical cancer research : CR - 12 Jan 2022
Amin Rada, Braza Mounia S
Abstract excerpt
Follicular lymphoma (FL) is a B-cell non-Hodgkin lymphoma of germinal center (GC) origin with a distinctive tumor microenvironment (TME) and a unique spectrum of mutations. Despite the important therapeutic advances, FL is still incurable. During B-cell development, the GC reaction is a complex multistep process in which epigenetic regulators dynamically induce or suppress transcriptional programs. In FL,...
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