Article

High-fat circulating nutrients promote growth and invasion in a 3D microfluidic tumor model of triple-negative breast cancer

2025-07-16

Abstract excerpt

Diet influences the levels of small molecules that circulate in plasma and interstitial fluid, altering the biochemical composition of the tumor microenvironment (TME). These circulating nutrients have been associated with how tumors grow and respond to treatment, but it remains difficult to parse their direct effects on cancer cells. Here, we combine a three-dimensional (3D) microfluidic tumor model with physiolo...

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Literature Corpus work: ec7b390c-7584-556f-b5e0-73c8d5ebce24
DOI: 10.1101/2025.07.10.664224

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