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Heterogeneity at the invasion front of triple negative breast cancer cells

1 Apr 2020

Abstract excerpt

Identifying better predictive and prognostic biomarkers for the diagnosis and treatment of triple negative breast cancer (TNBC) is complicated by tumor heterogeneity ranging from responses to therapy, mutational burden, and clonal evolution. To overcome the gap in our understanding of tumor heterogeneity, we hypothesized that isolating and studying the gene expression profile of invasive tumor cell subpopulations...

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PMID: 32238832
DOI: 10.1038/s41598-020-62516-8

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