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Adipocytes reprogram the proteome of breast cancer cells in organotypic three-dimensional cell cultures

7 Nov 2024

Abstract excerpt

While epidemiological evidence has long linked obesity with an increased risk of breast cancer, the intricate interactions between adipocytes and cancer cells within the tumor microenvironment remain largely uncharted territory. The use of organotypic three-dimensional (3D) cell cultures that more accurately mimic the spatial architecture of tumors represents an innovative approach to this complex issue. In the...

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PMID: 39505903
DOI: 10.1038/s41598-024-76053-1

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