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Article

The Angiogenic Secretome in VEGF overexpressing Breast Cancer Xenografts.

Scientific reports - 20 Dec 2016

Dore-Savard Louis, Lee Esak, Kakkad Samata, Popel Aleksander S, Bhujwalla Zaver M

Abstract excerpt

The plasticity of cancer cells and the fluidity of the tumor microenvironment continue to present major challenges in the comprehensive understanding of cancer that is essential to design effective treatments. The tumor interstitial fluid (TIF) encompasses the secretome and holds the key to several of the phenotypic characteristics of cancer. Difficulties in sampling this fluid have resulted in limited...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27995973
DOI: 10.1038/srep39460
PMCID: PMC5171865

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