Article
Hemidesmosomes regulate epidermal differentiation during embryogenesis
2025-10-02
Abstract excerpt
<h4>ABSTRACT</h4> In skin epidermis, integrins mediate adhesion of basal keratinocytes to the underlying basement membrane. While high expression of integrins has been correlated with stemness, there is limited direct evidence that integrins mediate keratinocyte retention within the basal layer. Here, we generate mosaic, epidermal-specific loss of integrin-β4 (encoded by Itgb4 ) or its ligand, laminin-α3β3ɣ2 (...
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Identifiers and source
- Literature Corpus work
- ec6792b3-16bd-5f83-a855-be9f5d4472d0
- DOI
- 10.1101/2025.10.01.679770