Article

Effects of TP63 Mutations on Keratinocyte Adhesion and Migration

2023-05-05

Abstract excerpt

<h4>ABSTRACT</h4> The goal of this study was to investigate the molecular mechanisms responsible for the formation of skin erosions in patients affected by Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (AEC). This ectodermal dysplasia is caused by mutations in the TP63 gene, which encodes several transcription factors that control epidermal development and homeostasis. We generated induced pluripo...

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Literature Corpus work: fa696303-d6e4-5734-9429-abb2d280cd1c
DOI: 10.1101/2023.05.04.539104

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