Article

Suppression of cyclooxygenase-2 predisposes to heart failure with preserved ejection fraction

2024-09-30

Abstract excerpt

Heart failure (HF) is one of the most strongly associated adverse cardiovascular events linked to the use of cyclooxygenase (COX)-2 selective and non-selective nonsteroidal anti-inflammatory drug (NSAID). Nevertheless, it remains uncertain whether NSAID exposure is more likely to lead to heart failure with reduced ejection fraction (HFrEF) or preserved ejection fraction (HFpEF). In adult mice, postnatal genetic de...

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Literature Corpus work: ec220c5e-4d97-55d2-830d-4238474424ed
DOI: 10.1101/2024.09.28.615616

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