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Article

Genetic polymorphisms of interleukin-16 and risk of knee osteoarthritis.

PloS one - 1 Jan 2015

Luo Shi-Xing, Li Shan, Zhang Xue-Hui, Zhang Jun-Jing, Long Guang-Hua, Dong Gui-Fu, Su Wei, Deng Yan, Liu Yanqiong, Zhao Jin-Min, Qin Xue

Abstract excerpt

BACKGROUND: Interleukin-16 (IL-16), a pleiotropic cytokine, plays a fundamental role in inflammatory diseases. This study investigates the association between IL-16 polymorphisms and the risk of knee osteoarthritis (OA) in a Chinese population. METHODS: The IL-16 rs11556218, rs4072111, and rs4778889 polymorphisms were determined in 150 knee OA cases and 147 healthy controls through polymerase chain...

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Identifiers

PMID: 25954818
DOI: 10.1371/journal.pone.0123442
PMCID: PMC4425433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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