Article

Donor monocyte-derived macrophages promote human acute graft versus host disease

2019-09-30

Abstract excerpt

Myelopoiesis is invariably present, and contributes to pathology, in animal models of graft versus host disease (GVHD). In humans, a rich inflammatory infiltrate bearing macrophage markers has also been described in histological studies. In order to determine the origin, functional properties and role in pathogenesis of these cells, we isolated single cell suspensions from acute cutaneous GVHD and subjected them t...

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Literature Corpus work: ebbdf25d-c26b-52ab-afd6-aa9ebf4b5676
DOI: 10.1101/787036

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