Article
Mass cytometry deep phenotyping of human mononuclear phagocytes and myeloid-derived suppressor cells from human blood and bone marrow.
Journal of leukocyte biology - 1 Aug 2017
Roussel Mikael, Ferrell P Brent, Greenplate Allison R, Lhomme Faustine, Le Gallou Simon, Diggins Kirsten E, Johnson Douglas B, Irish Jonathan M
Abstract excerpt
The monocyte phagocyte system (MPS) includes numerous monocyte, macrophage, and dendritic cell (DC) populations that are heterogeneous, both phenotypically and functionally. In this study, we sought to characterize those diverse MPS phenotypes with mass cytometry (CyTOF). To identify a deep phenotype of monocytes, macrophages, and DCs, a panel was designed to measure 38 identity, activation, and polarization...
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