Article
Immature monocytes from G-CSF-mobilized peripheral blood stem cell collections carry surface-bound IL-10 and have the potential to modulate alloreactivity.
Journal of leukocyte biology - 1 Oct 2006
Fraser A R, Cook G, Franklin I M, Templeton J G, Campbell M, Holyoake T L, Campbell J D M
Abstract excerpt
Production of the anti-inflammatory cytokine IL-10 by monocytes has been implicated as a probable negative regulator of graft-versus-host disease (GvHD) in patients undergoing allogeneic stem cell transplants (SCT). Monocytes from G-CSF-mobilized peripheral blood stem cell (gmPBSC) collections ha...
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