Plasma Proteomic Profiling Reveals Distinct Signatures of Chest CT Phenotypes in Sarcoidosis

Abstract excerpt

<h4>Background</h4> Sarcoidosis is a granulomatous disease of unknown cause with a highly variable clinical course. The inability to predict progressive inflammation, fibrosis, or both underscores the limited understanding of the underlying molecular mechanisms. <h4>Objective</h4> We aimed to identify novel protein signatures associated with distinct pulmonary phenotypes of sarcoidosis, including progressive inf...

Topics

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• Bronchoalveolar Lavage Fluid
• Case-Control Studies
• Disease Progression
• Phenotype
• Pilot Projects
• Proteins
• Sarcoidosis and Beryllium Toxicity Research
• Sarcoidosis, Pulmonary

Identifiers and source

Literature Corpus work

eba9e90a-9d3b-5eda-a08f-e2d111f33913

DOI

10.1101/2025.06.24.661339