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Transcriptomics of bronchoalveolar lavage cells identifies new molecular endotypes of sarcoidosis

3 Jun 2021

Abstract excerpt

BACKGROUND: Sarcoidosis is a multisystem granulomatous disease of unknown origin with a variable and often unpredictable course and pattern of organ involvement. In this study we sought to identify specific bronchoalveolar lavage (BAL) cell gene expression patterns indicative of distinct disease phenotypic traits. METHODS: RNA sequencing by Ion Torrent Proton was performed on BAL cells obtained from 215...

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PMID: 34083402
DOI: 10.1183/13993003.02950-2020

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