Article
Single Cell Transcriptome Signatures of Sarcoidosis in Lung Immune Cell Populations
2025-01-22
Abstract excerpt
<h4>ABSTRACT</h4> <h4>Rationale</h4> To identify cell specific molecular changes associated with sarcoidosis risk and progression, we aimed to characterize the cellular composition, gene expression patterns, and cell-cell interactions in BAL cells from patients with sarcoidosis (both progressive and non-progressive) and healthy controls. <h4>Methods</h4> Single cell RNA-seq data were collected on 12 sarcoidosis...
Topics
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- Cardiac tumors and thrombi
- Cytokine Signaling Pathways and Interactions
- Extracellular vesicles in disease
- IL-33, ST2, and ILC Pathways
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lung Cancer Treatments and Mutations
- Phagocytosis and Immune Regulation
- Sarcoidosis and Beryllium Toxicity Research
Identifiers and source
- Literature Corpus work
- 427f720a-dda3-5747-96d6-587f4e9ff2be
- DOI
- 10.1101/2025.01.20.633917
