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Article

Multi-omic signatures of sarcoidosis and progression in bronchoalveolar lavage cells

30 Jul 2024

Abstract excerpt

BACKGROUND: Sarcoidosis is a heterogeneous granulomatous disease with no accurate biomarkers of disease progression. Therefore, we profiled and integrated the DNA methylome, mRNAs, and microRNAs to identify molecular changes associated with sarcoidosis and disease progression that might illuminate underlying mechanisms of disease and potential biomarkers. METHODS: Bronchoalveolar lavage cells from 64 sarcoidosis...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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PMID: 39080656
DOI: 10.1186/s12931-024-02919-7

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