Plasma Proteomic Profiling Reveals Distinct Signatures of Chest CT Phenotypes in Sarcoidosis

Abstract excerpt

<title>Abstract</title> <p>Sarcoidosis is a granulomatous disease of unknown cause with a highly variable clinical course. The inability to predict progressive inflammation, fibrosis, or both underscores the limited understanding of the underlying molecular mechanisms. This study aimed to identify novel protein signatures associated with distinct pulmonary phenotypes of sarcoidosis, including progressive inflamma...

Topics

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• Bronchoalveolar Lavage Fluid
• Case-Control Studies
• Disease Progression
• Phenotype
• Pilot Projects
• Proteins
• Sarcoidosis and Beryllium Toxicity Research
• Sarcoidosis, Pulmonary

Identifiers and source

Literature Corpus work

5d95f0e4-22a2-519a-9935-bbb991dde897

DOI

10.21203/rs.3.rs-7358697/v1