Article

Molecular rhythm alterations in prefrontal cortex and nucleus accumbens associated with opioid use disorder

2021-10-09

Abstract excerpt

Severe and persistent disruptions to sleep and circadian rhythms are common features of people with opioid use disorder (OUD). Preclinical findings suggest altered molecular rhythms in the brain are involved in opioid reward and dependence. However, whether molecular rhythms are disrupted in brains of people with OUD remained an open question, critical to understanding the role of circadian rhythms in opioid addic...

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Literature Corpus work: eb924c2a-7a95-5649-8e15-8b465284eae3
DOI: 10.1101/2021.10.07.463568

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