Article

Local clocks within human tissues reveal widespread 24-hour rhythms in gene expression

2026-03-26

Abstract excerpt

Circadian clocks govern the 24-hour rhythmic activity of organs across the human body and these nycthemeral rhythms are critical for human physical and mental health. Here, we analysed 14,886 samples across 45 human tissues and inferred tissue-specific local phases using CHIRAL to define the rhythmic transcriptome. Local phase inference identified a median of 5,747 rhythmic transcripts across tissues, including 5,...

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Literature Corpus work: ee0b460a-f646-5a74-85c1-e42bdb891511
DOI: 10.64898/2026.03.24.713830

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