Article
The role of CLOCK gene in psychiatric disorders: Evidence from human and animal research.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Mar 2018
Schuch Jaqueline B, Genro Julia P, Bastos Clarissa R, Ghisleni Gabriele, Tovo-Rodrigues Luciana
Abstract excerpt
The circadian clock system drives daily rhythms in physiology, metabolism, and behavior in mammals. Molecular mechanisms of this system consist of multiple clock genes, with Circadian Locomotor Output Cycles Kaput (CLOCK) as a core member that plays an important role in a wide range of behaviors....
Topics
- Animals
- CLOCK Proteins
- Circadian Clocks
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Genomics
- Humans
- Mental Disorders
- Models, Animal
- Polymorphism, Single Nucleotide