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The Crohn’s disease-associated <i>Escherichia coli</i> strain LF82 rely on SOS and stringent responses to survive, multiply and tolerate antibiotics within macrophages

2019-02-18

Abstract excerpt

Adherent Invasive Escherichia coli (AIEC) strains recovered from Crohn's disease lesions survive and multiply within macrophages. A reference strain for this pathovar, AIEC LF82, forms microcolonies within phagolysosomes, an environment that prevents commensal E. coli multiplication. Little is known about the LF82 intracellular growth status, and signals leading to macrophage intra-vacuolar multiplication. We us...

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Literature Corpus work
4aeb6197-56e0-553b-9d16-0f4a81c00818
DOI
10.1101/551226
Open publication

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