Article

Large-scale proteomics analysis of five brain regions from Parkinson’s disease patients with a GBA1 mutation

2023-06-13

Abstract excerpt

<title>Abstract</title><p>Despite being the second most common neurodegenerative disorder, little is known about Parkinson’s disease (PD) pathogenesis. A number of genetic factors predispose towards PD, among them mutations in<italic>GBA1</italic>, which encodes the lysosomal enzyme acid-β-glucosidase. We now perform non-targeted, mass spectrometry based quantitative proteomics on five brain regions from PD patien...

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Literature Corpus work: eb50bab5-e3f3-5eec-b515-ce5d1241b1e4
DOI: 10.21203/rs.3.rs-3028475/v1

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