Article

Rho GTPase transcriptional activity and breast cancer risk: A Mendelian randomization analysis

2020-12-02

Abstract excerpt

<h4>Background</h4> Rho GTPases are a family of 20 intracellular signalling proteins that influence cytoskeletal dynamics, cell migration and cell cycle progression. Rho GTPases are implicated in breast cancer progression but their role in breast cancer aetiology is unknown. As aberrant Rho GTPase activity could be associated with breast cancer, we aimed to determine the potential for a causal role of Rho GTPase g...

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Literature Corpus work: eb4b121c-42e7-5553-8aea-edb6b9b70a20
DOI: 10.1101/2020.12.01.20241034

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