Article
Rho proteins and cancer.
Breast cancer research and treatment - 1 Mar 2004
Ridley Anne J
Abstract excerpt
The Rho family of GTPases has been intensively studied for their roles in signal transduction processes leading to cytoskeletal-dependent responses, including cell migration and phagocytosis. In addition, they are important regulators of cell cycle progression and affect the expression of a number of genes, including those for matrix-degrading proteases implicated in cancer invasion. So far, the expression of...
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