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Sex hormone binding globulin and risk of breast cancer: a Mendelian randomization study

9 May 2019

Abstract excerpt

BACKGROUND: There are observational data suggesting an inverse association between circulating concentrations of sex hormone binding globulin (SHBG) and risk of postmenopausal breast cancer. However, causality is uncertain and few studies have investigated this association by tumour receptor status. We aimed to investigate these associations under the causal framework of Mendelian randomization (MR). METHODS: We...

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PMID: 31143958
DOI: 10.1093/ije/dyz107

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