Article

Screening for pro-adhesive compounds and their relevance as therapeutic approach in Arrhythmogenic Cardiomyopathy

2025-03-25

Abstract excerpt

<h4>Background</h4> Arrhythmogenic Cardiomyopathy (ACM) is one of the major causes of sudden cardiac death in young adults. With the underlying patho-mechanisms not well understood, current therapeutic approaches for this genetic disease are solely symptomatic. A recent study demonstrates that loss of cell-cell adhesion is an important initial step leading to ACM. Because loss of cell-cell adhesion is considered...

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Literature Corpus work: eb2dc69a-8521-522e-ab66-a547118dc3ea
DOI: 10.1101/2025.03.23.643549

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