Article

Challenges in Using ctDNA to Achieve Early Detection of Cancer

2017-12-21

Abstract excerpt

Early detection of cancer is a significant unmet clinical need. Improved technical ability to detect circulating tumor-derived DNA (ctDNA) in the cell-free DNA (cfDNA) component of blood plasma via next-generation sequencing and established correlations between ctDNA load and tumor burden in cancer patients have spurred excitement about the possibilities of detecting cancer early by performing ctDNA mutation detec...

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Literature Corpus work: eb1c330c-e520-5deb-a9f1-33f97704166e
DOI: 10.1101/237578

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