Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical relevance of blood-based ctDNA analysis: mutation detection and beyond

24 Sept 2020

Abstract excerpt

Cell-free DNA (cfDNA) derived from tumours is present in the plasma of cancer patients. The majority of currently available studies on the use of this circulating tumour DNA (ctDNA) deal with the detection of mutations. The analysis of cfDNA is often discussed in the context of the noninvasive detection of mutations that lead to resistance mechanisms and therapeutic and disease monitoring in cancer patients....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Lung Cancer Treatments and Mutations
Share to Renal cell carcinoma treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32968207
DOI: 10.1038/s41416-020-01047-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical relevance of blood-based ctDNA analysis: mutation detection and beyondPMID 32968207Read ↗

The feasibility of using mutation detection in ctDNA to assess tumor dynamics.Semantic proximity Read ↗

A field guide for cancer diagnostics using cell-free DNA: From principles to practice and clinical applications.Semantic proximity Read ↗

Strategies for improving detection of circulating tumor DNA using next generation sequencing.Semantic proximity Read ↗

Detection of Circulating Tumor DNA in Plasma Using Targeted Sequencing.Semantic proximity Read ↗

Diagnostic and Therapeutic Potential of Circulating-Free DNA and Cell-Free RNA in Cancer ManagementSemantic proximity Read ↗

ctDNA as a Cancer Biomarker: A Broad OverviewSemantic proximity Read ↗

Identification of circulating tumour DNA (ctDNA) from the liquid biopsy results: Findings from an observational cohort studySemantic proximity Read ↗

ctDNA as a cancer biomarker: A broad overview.Semantic proximity Read ↗

Clinical application of circulating tumor DNA in metastatic cancers.Semantic proximity Read ↗

Exploring the Role of Circulating Cell-Free DNA in Disease Diagnosis and TherapySemantic proximity Read ↗

Circulating DNA in solid organ cancers-analysis and clinical application.Semantic proximity Read ↗

Review of the clinical applications and technological advances of circulating tumor DNA in cancer monitoringSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.