Article
The feasibility of using mutation detection in ctDNA to assess tumor dynamics.
International journal of cancer - 15 Jun 2017
Yi Xin, Ma Jianhui, Guan Yanfang, Chen Rongrong, Yang Ling, Xia Xuefeng
Abstract excerpt
For many decades it has been known that tumor DNA is shed into the blood. As a consequence of technological limitations, researchers were unable to comprehensively characterize circulating DNA. The advent of ultrasensitive and highly specific molecular assays has provided a comprehensive profile of the molecular characteristics and dynamics of circulating DNA in healthy subjects and cancer patients. With these...
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