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PBP1A and LdtJ support cell envelope homeostasis and impact selection of Colistin-resistance in <i>Acinetobacter baumannii</i>

2026-04-11

Abstract excerpt

The multilayered cell envelope of Acinetobacter baumannii is an essential structure that maintains cellular integrity and protects the bacterial cell against external stresses and antibiotics. It consists of an inner membrane, a thin peptidoglycan (PG) layer and an asymmetric outer membrane (OM) enriched in lipooligosaccharide (LOS), whose lipid A moiety is the target of colistin, a last-resource antibiotic. Alth...

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Literature Corpus work
eafdc9a8-5b02-5e55-b985-52bb664d9aad
DOI
10.64898/2026.04.09.717377
Open publication

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